Wow, an interesting 'way off the label' use of Naltrexone. Its value at low doses ( one low dose before bed) is to enhance the immune system by causing a short increase in dopamine and enkephalin. I can see how it might give very short term pain relief but am confused as to how it can effect PCS systems besides pain.

There would be a small mood enhancing from the endorphins which are also helpful for relaxation.

At present time, there is no drug approved for the treatment of PCS. Doctors often try to treat individual symptoms such as depression or anxiety or head ache.

Bud, Topamax and depakote are both for seizures. Are you being treated for seizures? Topamax is sometimes used for migraines, too.

What new meds has your neuro put you on? Have you done anything to improve your brain's nutrition? Omega 3's, B-6, B-12, folic acid, D3, anti-oxidants, etc? The injured brain is polluted with the byproducts of the injury and needs extra help and purging itself of these toxins before it can do much to recover/heal.

Your concussion history suggests that your brain has hit its critical mass of injury and will need serious nutritional and behavioral discipline to get better.

Your Verapamil is just a blood pressure medication likely prescribed to help lessen your head aches which are often due to blood pressure levels that the brain is not tolerant of. PCS can cause the body to mis-regulate blood pressure and be overly sensitive to even moderate levels of blood pressure.

Ask your neuro if you can take a couple baby aspirin before bed? It will thin your blood so that you will be less prone to morning head aches that result from early morning blood pressure increases.

Let us know how you are doing. There are plenty here who have lived with your symptoms.

My best to you.