Michael, you mentioned supplements affecting hydrogen. I find it very interesting that the abstract "ashlelyk" posted on the thread concernig the BBB noted that the neruoprotective dynorphin opioid peptide and naloxone share several common chemical properties--2 of them being hydrogen bond acceptor and hydrogen bond donor. One of your postings discussed a supplement consisting of manganese and hydrogen --do you take any other supplements for their hydrogen content or effect upon hydrogen (am reluctant to use anything with manganese)? thanks, madelyn