I take dextromethorphan,DM, readily available in over-the-counter cough syrups as dextromethorphan HBr. It has the same activity decreasing glial cell-mediated inflammation and neurodegeneration as naloxone and naltrexone which are available only by prescription. I take 5 to 8 mg of DM each night just before bedtime. I also take 450 mg generic sinemet, 100mg amantadine and 1000mg of CoQ12 each day.

I began this regimen two years after Dx, after starting at Dx on sinemet and amantadine. I do not think my symptoms have progressed since that time

Robert