I have heard that whether you are a slow or fast metabolizer of meds makes all the difference. They think I am a slow metabolizer because meds affect me way too much. Last time I was given a 1/2 of a child's dose of novacaine for a filling procedure and it numbed my tongue, one side of my ear, jaw and head, and most of one arm. The doc was totally baffled and of course this was all before my diagnosis and hearing that it's on a "no" list. I felt like crap for days after and had no idea why....

debra