[/QUOTE]I am on the drug acetazolamide.
Has anybody had more than one spontaneous leak? If so, did it happen at the same time? Are you on this medication?

Any other insights would be great....[/QUOTE]

Yes, I have taken acetazolamide continuously for over a year. At one time I was up to four caps - now I am at two caps around 1400 - which is when most of my daytime headaches come. I have had too many spontaneous leaks to count **sigh** sorry - once they started sealing some of the leaks up pressure would started to build and then new leaks would start up again... **sigh**