"To decrease the amount of dopamine needed as a precursor for epinephrine and norepinephrine, thereby helping to preserve dopamine, you can increase the efficiency of epinephrine. This will result in less depletion of dopamine."

Hi Imad,

I couldn't agree more with this doctor. We run out of norepinephrine like we run out of dopamine, which, in turn causes an imbalance of acetylcholine [initiates muscle movement - goes berserk thus tremor, bradykinesia, etc.] and GABA, the regulator of adrenalin and over firing.

i made a mistake in my interpretation. Seems reuptake has been studied and nortriptyline does lower acetycholine but it inhibits the reuptake of norepinephrine, which helps to balance the norepinephrine and seratonin. My bad sorry!