I have been looking for information concerning B6 toxicity for months and stumbled on this forum. Good information given. I have been running a medical practice for 21 years for chronically ill patients. I discovered B6 toxicity by accident in Spring of 2010. I developled PN (severe sensory) to the point I was in severe burning pain. Few physicians are aware of the dangers of this. Many patients are taking low doses and the levels go over 130. (ref range 2.2-2.8). Noticed the higher the blood level, the worse the symptoms. Can't find any expert to address this or how to pull it out. Talk with a famous PHD who writes many books on Vitamins and never heard of it!! Began to wonder if it was an enzyme deficiency and the contacts were clueless. Next I suspected the liver. Any information on those going through this will be so greatly appreciated. My levels are rising again (double) and theP N is starting again. Few meds help with it, but ask you doc about clonazepam or Neurontin for painful neuropathy. Anyone got good news on recovery time? Again, thank you.