Annie's right. Long discussion with my doc re: my dosages and activity. I was given a max amount that can be taken in a 4 hour period - - along with guidelines about how to approach the dosing before activity (ie. in my case golf in hot weather).

But I was also advised about what to look for and warned that exceeding the '4 hour max amount' could result in a cholinergic crisis...or even a heart attack!

That got my attention Talk to your doc!