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Originally Posted by stevem53
What Ive been wondering is this..DM is a dopamine reuptake inhibitor..I wonder if it causes the Sinamet to work more efficemtly
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But what really got my interest was the "warning" about resensitizing of the receptor system. One way to skin the PD cat is to flood the system with dopamine figuring some will get through. That's more or less the sinemet approach.
The other is to optimize the receptor sensitivity and make a little dopamine go farther, which may be what is happening in part.
-Rick