Thread: Elavil.........
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Old 03-05-2011, 07:31 AM
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mrsD mrsD is offline
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

TCA's prolong QT. So it would be listed as interacting with all drugs in the various lists that do that too.

Here is more on QT prolongation:
http://www.azcert.org/
This has evolved into a very nice website complete with
revolving graphic illustrating what the QT interval is.

In the small doses like 10-25mg a day, this is much less an issue than past 50mg or so. 50mg is borderline.

TCAs like Elavil were often a method of suicide in depressed patients, and often was successful. (poor useful interventions for it).

With the advent of SSRIs ...which do not have this deadly potential for overdose...doctors rapidly switched to them, and left TCAs in the dust for high dose use.
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JoanB (03-05-2011), stagger (03-05-2011)