When I was "firmly" diagnosed with SPMS, which it ends up I was misdiagnosed, I chose to use Avonex because it was a once a week injection. All well and good, BUT it requires and intramuscular injection and you suffer flu symptoms for the next 24 to 48 hours.

As a direct result I would take the shot on Friday nights after prepping with Aleve before and after injection. I did this for over 2 years then learned of the misdiagnosis. I was never honestly convinced there was empirical research supporting any short or long term value to this type of medication. Even the neuro said it was the best thing they could offer even though the actual outcome is unknown.

Bottom line, taking Copaxone every single day does get very old very fast. Why not take a break and as mentioned, talk with your neuro about other alternatives. At least THAT can't hurt, right?