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Originally Posted by Conductor71
Steve,
That is wonderful for you...what a relief. I think that your symptoms are subsiding because Ambien releases GABA into our brains. GABA like dopamine is an inhibitor, so in our case it is picking up the slack. It's GABAs job to rather scan for overfiring synapses and to tone them down...hence the symptom relief.
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It was a welcomed relief!!..I kinda figured there was some sort of inhibitor in it
My problem is the nagging uncomfortable feeling I experience in my entire body, after I go "off" from Stalevo for the night..I can deal with the shuffling, and the brandykinesia, but being so uncomfotable that I have to wear sweatpants cuz wearing jeans drives me bonkers, is more than I can deal with..It will drive one insane after a while
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I get the same effect with Klonopin which works in similar fashion; however, it is highly addictive as is Ambien, so look out. You may want to ask your doc about the CR which will last you through the night and safer to use long term
from what have read.
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I started out on Klonopin 3/4 mg for sleep..It worked for about 6 months, and I knew that my options were either more Klonopin, which I did not want to do, or try a different med..So my neuro Rx-ed Amien, which was great for addressing the sleep issue, consistantly..Ive been using it for about a year now..
Then the uncomfort set in almost over night approx 6 months later, so my neuro Rx-ed Valium 5 mg once daily at 6:00 pm, Ambien at midnight..For 3 months the Valium worked great, then lost its effect, and I began to notice this release from the discomfort after midnight every night..The only thing that had changed in my condition, was the ingestion of Ambien after midnight, so I put 2+ 2 together, and experimented replacing the one dose of Valium with the Ambien..I got a release in 30 minutes, and was nearly symptom free at about 12:30 am after the midnight dose..It didnt surprise me that it worked, but I was taken aback by how well it did work..I have done this about 4 times with mixed results, but all positive results nonetheless
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I have an unopened bottle of Ambien CR but have been afraid to take it as it can result in sleep actions. More than just sleepwalking...a person gets up to cook, draw a bath, drive the car...all while sleeping! I am hoping that the CR version is safer in this regard too.
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My neuro mentioned CR briefly, but didnt get into it
Guess I'll throw out the anchor out at betime if I try it
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Also, your news is exciting because it proves that the Neurologix is on the right track with its new PD therapy using GABA to help restore balance among our neurotransmitters. They are in Phase II clinical trials.
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Thanks for the link!...I willl check it out
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You are proof that they are definitely onto something big...I imagine we may still need levodopa but less of it. Kind of same ideal outcome minus the freaky surgery and lead wires. Plus I like how Neurologix is taking what we already have in us and harnessing its power to in a sense heal us.
Laura
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Im all for alternatives to surgery and wires..Ive seen miracles, and disasters with DBS..Not quite ready to embrace going down that road yet