Quote:
Originally Posted by mrsD
The mechanism that aspirin and NSAIDs use that promotes bleeding is not only local. It is metabolic throughout the whole body affecting cytokine production everywhere as an anti-inflammatory. This whole body effect also reduces platelets, and that is how aspirin can prevent blood clots. In people with damaged intestines, bleeding will result, because of this platelet action. So the buffering is only good as a temp measure.
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That's what happens to/with me. Long gross story short, taking aspirin (buffered or otherwise) or any NSAID other than meloxicam more than once a week will cause intestinal bleeding.
We once had a border collie who was prescribed aspirin for a couple days for arthritis (too stiff to get up) and it gave her intractable nosebleeds, because it impeded clotting.
It's still a miracle drug of sorts; they're still finding out new information about it and its benefits, but every silver lining has a cloud....
Doc
Doc