I started Imuran at the end of Nov and haven't noticed any change. I just finished IVIG the doctor ordered to hold me until Imuran kicks in. He said 3-6 months for the Imuran. I also take 3 60mg tabs of Mestinon during the day and 180 time release mestinon at night. So far nothing has helped me. My next appt is end of month and will see what is next.
Hope it helps you.
Mike