When I was new to mestinon I had spasms when they moved me up to 75mg every 6 hours from 60mg. Because of how that worked for me I wonder if you are on too much for some reason. Everyone is different and affected differently.

What I mean by this is that the higher amount affected my diaphgram area muscles mostly. It would only hit when I laid down and when I coughed, something that would affected that muscle harder. I had had a mild version of this when on 60mg as I was first getting used to the medication but it stopped. AT 75mg tho it was a massive reaction that literally scared me. The spasms that would come on in my diaphgram where as if this normally strong big muscle were a Jello mould and it was smacked hard by something setting into this wild jumping.

Yes I think that is one of the weaker places in my body and it was the first place that was strongly hit during my crisis but it is also a place that gets a harder use when I cough or strain to lay down in bed.

Annie59