I do take LDN and have for several years now......without my Neuro's blessing I might add. But, I've been healthier than I was while on a DMD. And I don't have to contend with all the side effects. Lot's of folks here have been "DMD-Free" for years. Even if I didn't have MS I believe I would still take LDN for all the other benefits it offers. Even the pharmacist where I get my LDN filled takes it and he doesn't have MS. Plus, it costs me out-of-pocket less than $200 per year while the DMD can get into the tens of thousands of dollars.