If the B3 is Niacin and not niacinamide form, yes that is enough to flush for some people. On an empty stomach it would be faster.
Niacinamide however, does not produce the flush and is in this form in most B-complex mixtures.
You can block the flush with an aspirin taken 1/2 hour before.
Also if you use ACE inhibitors, these release brandykinin also and would be additive with pure niacin. So smaller doses might produce a flush when they would not, if no ACE inhibitor was present.
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Weezie looking at petunias 8.25.2017
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