Hi Anthony - I know exactly how you feel. I also drive a smaller sedan that gets great gas mileage but seems to react to every little bump in the road!
Rough pavement is bad but what really works me are compressions. By this I mean when there is a slight incline in the road, usually before a bridge, then a quick drop-off on the other side. Driving over this at highway speeds causes a rapid up/down that I'm really sensitive to right now. Occasionally, I'll get a quick pain in my temple along with the "down".