I remember in Chicago a doc who prescribed accutane was killed by a patient a few years back. I don't recall the case exactly but I think the suspected murderer had a hist of mental problems and the accutane made him impotent. He got upset and killed the doc. I thought you had to have the ok from a psych to get the prescription. Also some of the endorsers for proactiv, have used accutane and lied about proactiv being responaible for their clear complexion.