Hi Gang:

Over the years, I have used Cymbalta with moderate success for Neuropathic pain (especially Small Fiber).

The only side effect that I have encountered is delayed orgasm, which is very frustrating.

I recently read online that "Bupropion" (or "Wellbutrin") was shown in a number of studies to be effective for neuropathic pain relief without the sexual side effects of Cymbalta.

It was also shown to be useful in weight loss as a nice side effect.

Can anyone who is knowledgable about this drug share their knowledge. Could this drug actually be an effective replacement for Cymbalta without the sexual side effects?

I know that it is not an "SNRI" like Cymbalta, so I was surprised to read that it may be effective for treating neuropathic pain as opposed to depression alone.

Many thanks!

David