I am amazed to read this - I have myclonus and my neurologist tells me he doesn't know how it started - but I know - I had a fall that injured two disks and after that came the myclonus - I am sure of it. I take mirapex - sometimes it is gone for weeks thancomes back full force - the "jerks" are so powerful I almost fall out of bed. I am anxious to learn more about botox - I will do anything to relieve myself of this - it is ruining my life. I have no one to talk to who understands inclujding doctors.