My 20 year old son developed hydrocephalus at birth following a severe meningitis infection and has been shunted all his life. He has traveled by air extensively since infancy and never experienced any noticeable problem as a result. He also frequently drives to mountain areas, hikes for days at a time and rock climbs at altitude. While his experience has been positive so far, I am always weary of this type of anecdotal advice. Each case is different and I always advise to obtain a professional opinion from a neurosurgeon whenever possible.