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Old 03-03-2007, 03:37 AM
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mrsD mrsD is offline
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Post This is an interesting thread...

There are other forms of DM you can use.

Delsym is pure DM in sustained release dosage form. Most pharmacies carry
it:
http://www.delsym.com/

Some people get nausea from the guaifenesin in Robitussin DM. So if you prefer single dose DM the Delsym is for you. But it costs more.

There are tablets also, with guaifenesin and DM 30mg sustained acting:
Mucinex DM
http://www.mucinex.com/pdf/Mucinex_DM.pdf
Some stores now have a generic available for this.

Kids abuse DM so if you begin to use it in high amounts, you may attract
attention in the store. Some pharmacies may have it behind the counter because of this. Coricidin HBR recently was targeted by abusers and is
often behind the counter now.

Very high dosing of DM can cause dissociative CNS symptoms and a peculiar
"buzz"...but in the doses mentioned here, that should not be a problem.

Here is more information:
http://www.nhtsa.dot.gov/PEOPLE/inju...methorphan.htm
Quote:
Drug Interactions: Should not be taken with Monoamine Oxide Inhibitors (MAOIs) and Selective Serotonin Reuptake Inhibitors (SSRIs) because of an apparent serotonin syndrome (fever, hypertension, arrhythmias). Should be used with caution in atopic children due to histamine release. Additive CNS depressant effects when co-administered with alcohol, antihistamines, psychotropics, and other CNS depressant drugs.
The serotonin reuptake is documented, but not common.

This is also interesting:
Quote:
Pharmacodynamics: Dextromethorphan acts centrally to elevate the threshold for coughing, and has no significant analgesic or sedative properties at antitussive doses. It is proposed that dextromethorphan is a glutamate and NMDA antagonist, and blocks the dopamine reuptake site. It may also increase 5HT 1A activity possibly via NMDA antagonism.
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