Quote:
Originally Posted by Conductor71
Krugen,
I agree with you, but my understanding is that much of what holds us back from progress in this area is the notion that we have sinemet, so what's the rush? There are several alternatives in trial that I started to mention because I was thinking "dopa hang up" when I first read that report. I could seriously see the GABA treatment by Neurologix and Adnosine receptor antagonists taking the place of what we have now. In the article, guess I really could not understand if dopamine therapy was being discouraged or encouraged but manipulated somehow. Speaking of Adnosine antagonists, the research has been around a while, enough to constitute a book!!
Adenosine Receptors and Parkinson's Disease
The question I have is why do these treatments slog through trials or never get approved? There is a thread started here that asks a similar question:
Why don't we have parallel tracking for other conditions?
Initially designed to help AIDS patients, parallel tracking makes drugs showing promising results in phase III of the IND process available to patients whose condition prevents them from participating in controlled clinical trials. Parallel tracking is similar to the treatment IND, a program started several years earlier.
A large part of the problem IMHO is that we have no unified voice questioning the status quo, so why do anything differently? It can take on average, fourteen years for a new treatment to make it through the pipeline, we don't have that kind of time to waste. We need to start demanding more of the scientific community and advocate for alternatives to dopa replacement.
Laura
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Laura
I totally agree with you. I will find out in May if I will make it onto the Cogane trial II, but the result of that trial is not due out until late 2012. Then how many more years ?
Who is to blame ?
The established Pharma companies that sell $ 3 Billion + to a captive audience with no incentive to produce a real 'cure'?
The bureaucrats that simply shuffle paper and wish to avoid any 'blame' sticking to them if drugs cause harm ?
The thousands of PWP who have no collective will or voice to embrace change ?
I suspect as with AIDS 'epidemic' and the resultant focused 'community' PR, it will only be when the costs of Alzheimers and PD become to big a drain on national budgets that the problem will be addressed.
Sighs