Like everything else about this disease - I think each person is different. I was diagnosed in 2000 and for the first 4-5 years, I took only Cellcept and Mestinon and continued to have a fairly normal life. In 2005, I had my first crisis and my thymectomy. I have had some good periods since then, but have gotten progressively weaker. I retired on disability in Nov 2010 because my breathing was so labored and my overall weakness progressed.

So for me, it took about 10 years from diagnosis to the point I couldn't work anymore, As I said, my belief is that it is personal to the individual.

Good luck with your journey!