First of all, I wanted to say I'm so sorry you are feeling that way. I can relate all too well. Some days, especially lately, I wonder why I'm even bothering with the therapies since I see no noticeable benefits.
American RSDHope has a page comparing and contrasing RSD and fibromyalgia, if you've not already seen it.
I'm not sure I'd go with a PCM's recommendation over the specialists, but then again, with my particular PCM, I might, since she is so involved in my day to day care. Did your PCM mention why she wanted you to go to Mayo as opposed to Cleveland? I guess I can see that it would make sense if you are still trying to find a diagnosis.
Aquatic therapy is nice. I'm not sure whether it's actually helpful or not, but I'm not sure that anything I do helps. Then again, who knows how bad it would be if I stopped all of the meds and therapies. Hard to say.
Have you told your PCM about your feelings re: life in general? Depression and anxiety are both common in RSD patients. She might be able to help with it.