I mentioned this question about DM and PD to Anne Frobert, the French MD and PWP who posted a few times on banding. She pointed out that levodopa has at least two effects. One is short term and helps us move. The other longterm one is dangerous and leaves us damaged.

It is possible that a similar dual action (thought hopefully with a better outcome) is at work here. What I mean is that the benefits that Steve is experiencing may be totally unrelated to what Robert is observing and I suppose that Dr. Hong could be looking at a third process. Short term symptom relief is something we can readily observe. Longterm effects, both good and bad, are beyond our capabilities to evaluate.

Something just wafted across my brain as I was thinking about the possibility of the higher dosage required for one negating the the other. There was something, and I think it was curcumin, that was effective at lower doses but lost some of its benefits as dosage increased. It might be acting on the same systems.