My grandmother had pervasive loss of skin pigmentation and my first cousin [our mothers were sisters and daughters of this grandmother) has no pigmentation at all. She is completely white. She is 68. I have little blotches but nothing too large,yet it is there. This is something that should be looked into seriously because it all started in the 80s and i noticed it during my second pregnancy.

I think i have every biomarker mentioned that you don't have to test for, Hopefully, the upcoming NIH eval will fill in some blanks.