Ave8ergirl was Clinical Trialing Revimmune but I do not think it was successful for her. Dr Douglas Kerr was active in HY/Cy at Johns Hopkins and Revimmune but he is no longer at JH. Last I could find was a newspaper article on HY/CY at JH by Dr. Kaplan from 2009, but I have no idea of anything afterwards. Hy/Cy is a really hard one, the Chemo makes you sick, can make all your hair fall out and lower your immune system. I'm not sure there were consistent, long lasting results. I'm always hopeful about MS treatments but not very convinced, but PPMS seems very different from RR and not receptive to treatments. I tried Novantrone (another chemo) but all it did was make me throw up.