Guess it depends on your disability...One good thing about working from home vs. in the office is that you when things get too bad you can always take a break and lay down etc. whenever you need too. Then again, it still didn't work too good for me when my job set me up at home because I found myself laying down more than I was working because I was too weak to sit at the computer for more than an hour at a time no matter where I was on my worse days back then.
Don't know if I would try that to be honest with you. But that's just me, I've always been known to be extra cautious.