Long story short-I have diabetic neuropathy and every kind of "nerve" medication doesn't work. I have seen 2 neurologists and the second one referred me to a pain clinic, which I went to today. The doctor prescribed me something called Metanx (which he said could take at least 3 months to even start to work, if it works) and also Norco 5-325 2 to 3 times a day. Now I have read that this dosage is similar to Vicodin 5-500 which I have had before for when my first neurologist gave me a few years ago. I have also had this Vicodin when I had my wisdom teeth taken out. Anyway, when I took these Norco today for my leg pain (I am only going to take it when they hurt badly as needed. Such as working or laying/walking for long periods of time) and it did nothing. I had no effects from it whatsoever, it was like taking Ibuprofen or aspirin-it had no effect on my paining legs. I don't know if people have better luck with the Vicodin? Or if it takes a couple of doses to kick in? I see him again next month and I am afraid that I might need a stronger dose? Which makes me uneasy because I am nervous to admit I need painkillers since I am such a young age, it's almost embarrassing. Or it makes me sound like a junkie, and I don't want that reputation. Anyway, any body's opinion/help/advice would really help me out. If anyone has experience with neuropathy and painkillers or just with Norco itself? Thank you so much.