My DX is idiopathic polyneuropathy with quite a bit of pain in my feet and legs. After trying just about everything else (Cymbalta, Lyrica, Neurotin, Tramodol, etc) my neurologist started me on Fentanyl (generic for Duragesic) a little over a month ago. I started at 12mcg/hr changing patches every 72 hours. After 2 weeks, she increased my dosage to 25mcg/hr every 72 hours. Now I'm at 25mcg/hr changing patches every 48 hours. Pain is better but not great yet. I imagine I'll go to 50mcg/hr next but I want to give the current dosage a chance to work.

These patches are a Schedule II Narcotic. Use as directed and there should be no problem. Changing your dosage without your doctor's advice can cause major problems both medically and legally.