Thread: inflammation
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Old 05-05-2011, 10:52 PM
Mark in Idaho Mark in Idaho is offline
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Mark in Idaho Mark in Idaho is offline
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Join Date: Feb 2009
Location: Somewhere near here
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15 yr Member
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The prednisone may be acting on inflammation or it may be just replacing some corticosteroids that are being under produced by the adrenal cortex.

<Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior.

* Glucocorticoids such as cortisol control carbohydrate, fat and protein metabolism and are anti-inflammatory by preventing phospholipid release, decreasing eosinophil action and a number of other mechanisms.
* Mineralocorticoids such as aldosterone control electrolyte and water levels, mainly by promoting sodium retention in the kidney.>

I would consider the prednisone to be symptom reducer but not necessarily a supporter or promoter of any healing mechanism. Hormone imbalances are common with PCS.

Be careful that you don't mistake 'feeling better' with recovery. When you can feel better without the prednisone, then you are recovering.
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