Medicine moves very slowly. I agree it is difficult who to believe.

Go to Grassrootshealth.net and see the list of doctors who support the new research.

Studies show very little risk of toxicity even from massive doses for long periods of time. The body of work that has been done in the past 10 yrs is quite large now.

I agree for MSers to follow the ultra high guidelines target (100) is a bit more worrisome than the recommendations that are more moderate (50-80). So look up the studies for MS recommendations specifically to help you decide. The only toxicity found, and that is anecdotal is elevated calcium and that can be tested for and monitored.

Studies keep rolling in for MS:
http://neurotalk.psychcentral.com/post767924-1.html

I will say both hubby and I feel so much better with D supplements. I used to get alot of sun on vacation and come back home with a deep tan, and feel great and by end of Sept the creeping awfuls would return for me (arthritis pain). Neither one of us has had an upper respiratory infection since increasing from 1000IU daily (which is what we used to take) for just over 2 yrs now.

Get tested, and decide what you will do. But staying really low is not going to be good for anyone, MSer or not.

I personally was skeptical years ago when the D information started rolling in. We started on 1000IU daily, increased to 2,000 next year, then 4000 and finally 5,000 and I still tested at 43! 5,000 seems to be good for both of us tho and we do get sun more than most people.
Now I am taking 10,000 IU one day and 5,000 the next and will get a retest in fall with my annual physical. Doctor wanted me to try and get a bit higher closer to 70.

I don't feel comfortable giving really high dose recommendations yet to people on these boards, esp the ultra high MS recommendations, so being monitored for doses over 5,000 IU daily D3 is still a prudent thing to do. Just remember, do not take high dose calcium products while on the high D. That is where you may get into trouble! The D will facilitate absorption of calcium so you should be okay with food sources.