The "reboot" is something new that's being tried in a few medical centers. Actually, it's only "new" to MG - it's essentially the same procedure used to do a bone marrow transplant for someone with leukemia. They harvest your bone marrow (I believe), you go through high-dose chemotherapy to completely kill your immune system, and then they reintroduce your bone marrow to rebuild your immune system, hopefully without the MG. Considering the risks associated with it, I think it's done more as a last resort for those who have tried everything else and had no success, instead of as a generally available treatment. I also understand that, even if it works initially, the MG can come back in the future, necessitating another "reboot" or treatment with other meds.