Welcome to NeuroTalk:

10mg is not an antidepressant dose of this drug. Amitriptyline and Nortriptyline have had recent studies showing they improve nerve damage.

Low dose use of these two drugs does not often impact depression. They are used for all sorts of chronic pain, headache pain and neuropathies. Antidepressant doses start at 50mg a day or more, and often go up to 300mg a day. These drugs are rarely used as antidepressants anymore.

Some actions on serotonin do affect signaling in the brain in the pain loops and low dose antidepessants may help in this area too. Don't expect much subjective antidepressant feelings at 10mg a day however. These drugs are not fast onset either, so expect at least 3 weeks to pass before you notice improvements. You may have side effects first before improvements occur.