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Old 05-19-2011, 06:45 AM
glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
Default There can certainly be--

--multiple factors contributing to the neuropathy.

But that IgG Kappa protein should be watched, and not only for possibility of blood disorders--any pararprotein, or monoclonal (M-protein) can cause neuropathy through interaction with nerve epitopes. The most common of these is actually demyelinating (as opposed to axonal, which small-fiber neuropathy by definition is)--the interaction of monoclonal antibodies with anti-MAG (myelin associated glycoprotein)--but people with paraproteins often have interactions with both larger and smaller fibers.

See:

http://neuromuscular.wustl.edu/antibody/mprotein.htm

http://neuromuscular.wustl.edu/antib...imdem.html#mag
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