Originally Posted by glenntaj

--multiple factors contributing to the neuropathy.

But that IgG Kappa protein should be watched, and not only for possibility of blood disorders--any pararprotein, or monoclonal (M-protein) can cause neuropathy through interaction with nerve epitopes. The most common of these is actually demyelinating (as opposed to axonal, which small-fiber neuropathy by definition is)--the interaction of monoclonal antibodies with anti-MAG (myelin associated glycoprotein)--but people with paraproteins often have interactions with both larger and smaller fibers.

See:

http://neuromuscular.wustl.edu/antibody/mprotein.htm

http://neuromuscular.wustl.edu/antib...imdem.html#mag