Hi Glen!
What are the various "multiple factors" that you feel are contributing to my neuropathy (I would assume that you feel my "IGG Paraprotein" is one)?
Keep in mind that I show no signs of demyelination based on multiple nerve conduction and EMG studies.
Thanks!
David
Quote:
Originally Posted by glenntaj
--multiple factors contributing to the neuropathy.
But that IgG Kappa protein should be watched, and not only for possibility of blood disorders--any pararprotein, or monoclonal (M-protein) can cause neuropathy through interaction with nerve epitopes. The most common of these is actually demyelinating (as opposed to axonal, which small-fiber neuropathy by definition is)--the interaction of monoclonal antibodies with anti-MAG (myelin associated glycoprotein)--but people with paraproteins often have interactions with both larger and smaller fibers.
See:
http://neuromuscular.wustl.edu/antibody/mprotein.htm
http://neuromuscular.wustl.edu/antib...imdem.html#mag
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