Hey Ayna. I tried rebif for 2-3 months and said enough. I no longer had the side effects (take at night and sleep it off) but Copaxone which I was on 3yrs prior had ZERO side effect, it just stopped working on me. I went to Tysabri. MS is still progressing on Ty + the dozen supps i take but i'd never go back to injections. Infuse every 28 days = easy. Zero sides from Ty for me. I swam 20 laps when i got home from last infusion.