For me serequel was not for the pain it was cause my mood was everywhere and also supposed to aid in sleep. For me it did not help with the sleep but may have helped with my mood. I was having outbursts of anger and up and down moods. I am better at that then I was but I also have learned how to cope better with things. So not sure. My friend who has RSD takes serequel and before barely slept and with it she sleeps so well. So it has helped her.
Cymbalta I was on 120 and now 60 and I don't feel any different. I had no issues with lowering it. Just make sure you follow what the doctor suggests