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Old 05-26-2011, 03:29 AM
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mrsD mrsD is offline
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Join Date: Aug 2006
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Here is a drug checker to use:

http://www.drugs.com/drug_interactions.html

Cymbalta is the only antidepressant with potential to damage the liver. It has a warning in this regard.
Quote:
There have been reports of hepatic failure, sometimes fatal, in patients treated with Cymbalta (duloxetine hcl) . These cases have presented as hepatitis with abdominal pain, hepatomegaly, and elevation of transaminase levels to more than twenty times the upper limit of normal with or without jaundice, reflecting a mixed or hepatocellular pattern of liver injury. Cymbalta (duloxetine hcl) should be discontinued in patients who develop jaundice or other evidence of clinically significant liver dysfunction and should not be resumed unless another cause can be established.

Cases of cholestatic jaundice with minimal elevation of transaminase levels have also been reported. Other postmarketing reports indicate that elevated transaminases, bilirubin, and alkaline phosphatase have occurred in patients with chronic liver disease or cirrhosis.
http://www.rxlist.com/cymbalta-drug.htm

Keep this in mind if you use combination drug therapies. They may be additive to the liver. This especially pertains to Tylenol.
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nsw43 (05-27-2011)