Yes, metformin changes reactions to food. In general it can reduce appetite, and sometimes cause a low grade nausea that results in avoidance of food in general. It has been used in various weight loss plans for this effect.
A good meal replacement can be a whey protein shake, with yogurt/ low glycemic fruits, and some flax oil. This will provide calories, and nutrients, and taste good. People will drink when they don't feel like eating. Avoiding sugar and using whole things in the smoothie controls insulin too.
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Weezie looking at petunias 8.25.2017
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