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Old 07-01-2011, 06:11 AM
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mrsD mrsD is offline
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Okay, I see the reference to ADHD medication....
Strattera is the first one listed, followed by the amphetamines.

I can see strattera, since it is related to SSRIs... and has QT risk.
But as far as the amphetamines go?
There are no metabolic connections (like with Strattera) but perhaps it is the stimulant properties themselves, that might complicate the action of the DM in the brain?
This quote from side effects of Nuedexta:
Quote:
agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting;
from http://www.drugs.com/nuedexta.html

The bolded words would be additive with any stimulant. Amphetamines do increase heart rate.

Interactions between drugs usually refer to metabolic interference, meaning raising or lowering levels in the blood, so that a drug may become inactive or toxic because of that metabolism.

Therapeutic effects are different, usually additive or synergistic physiologically meaning the drugs may affect the same systems in action.

What we have been discussing on this thread are metabolic interactions which lead to unexpected results (mostly cardiac).

The effects listed for amphetamines are similar to amphetamines + other stimulants. (caffeine for example).

Today, the drugs that are available are very complex chemically. And it is no surprise that the 4th leading cause of death in US is from prescribed medications or errors with them.

I think we are reaching a ceiling of sorts, where all medications are going to have to go thru a screening data base for patients, to avoid problems. All patients are going to have to be evaluated soon for liver enzyme potentials and genetic variances. There are people taking 10, 15, and even 20 drugs a day. I see them on boards frequently and saw them in real life every day!
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Last edited by mrsD; 07-01-2011 at 08:41 AM. Reason: adding clarification
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