I used to fly alot to go to my RSD doc. Make sure you take your pain meds & Xanax if you have a script. Cabin pressure sucks but not much you can do about it. When you reserve ticket, tell them you are disabled & need assistance....wheelchair, etc. I noticed that when we got one way tickets, we always got extra pat downs. They didnt care to even listen about the RSD. Once they lost my luggage, huge ordeal.....by end of night I was curled up in a ball on floor in baggage office crying to just go home. They found our bags & took me up to a nice hotel in the airport, but the damage was done.