Originally Posted by jackD

It is my understanding that after the water content of the stools is removed in the lower colon that the hard stools irritates the lining of the colon and stimulates a reaction that causes the sphincter nerves to relax and initiate an evacuation reflex movement.

In MS folks this does not happen because the nerves are not working properly.

Vinpocetine aids nerve conduction to smooth muscles.

jackD