Yes to all of the above
Just saw a new nuero doc last week and mentioned the swelling and he didnt even bother to look just said most people stay off there feet so even a visit to the doc can trigger swelling due to circulation issues. of course meds cause swelling as well.
neuropathy spreads and its what makes it so difficult to deal with mentally.
Some have had success with reversal but from what I see there aren't many.