Quote:
Originally Posted by lynn01
It's been awhile since I have been on the forum. I am just wanting a little information on hereditary neuropathy. I just had a second nerve conduction study done, a year from my last one and it showed improvement in the sensory nerves. My f-waves had some improvement but are still prolonged. But the motor nerve conduction velocity for my peroneal nerve really did not have much change except they were able to get a reading on my right side, that they did not get on the first test. My numbers for the motor conduction velocity are 33m/sec for the right and the left peroneal, it is supposed to be 43m/sec or higher to be considered normal. The compound muscle action potenials are supposed to be 4.0 or higher and mine are .63 left and .93 on the right for the peroneal nerves. My left tibial nerve velocity improved by 1 point, the right one is normal. He was thinking maybe and automune issue was going on. Because there was not any marked progression, he is leaning toward a genetic problem, he says they are very slow in progression. I do have high arches in my feet that he refered to as pes canvus on the report. I would say my feet have a higher than normal arch, but not extremely high. I can not afford genetic testing that he is suggesting. My neuropathy has demylinating and axonal features. Can there be remylinating of the covering of nerves in hereditary neuropathy that would cause the conduction velocity to show improvement in the sensory nerves. It is just so fustrating not knowing what is causing my problems. Any help would be greatly appreciated.
|
Hi,
I can only speak for CMT. Yes, in some types of CMT there can be remylinating of the covering of the nerves. However, I think it is rare. But they are learning more all of the time.
As you may know, CMT is a hereditary neuropathy for the most part. There can be a spontaneous mutation but that is rare. CMT is also know as Hereditary Motor Sensory Neuropathy (HMSN). There are many, many types of it and subtypes. DNA blood testing is very expensive if you have to do the whole panel of tests. CMT is often misdiagnosed even today. There is a medical alert list of drugs you should not take if you have CMT.
Some people have high arches, some have flat feet. Some CMTers legs look "normal" and others are like champagne bottles. Of course, it is a disease of the Peripheral Nervous System and so it can affect the hands, lower arms, etc. Anything outside of the Central Nervous System.
Check out PN Tips, Resources, etc. at the top of the page. You will find information concerning CMT.