conductor,
i think your're getting carried away. all neurological diseases are difficult to treat, if they were easy we wouldn't be having this discussion. it's impossible to selectively deliver drugs//genes to brain neurons except by surgery and that seems to be the road that research is taking, there have been at least 6 gene therapy trials for pd that have gotten to phase 2 and 5 have failed.
i was in a trial for sumanirole about 8 years ago, a dopamine agonist. in a county of over 1mill, 3 people volunteered. it ain't easy bringing even a dopamine replacement to market because it's very difficult to prove that it's better than existing products.

so complain all you want about sinemet, my impression is R&D ain't concentrating on pharmaceuticals for the very reasons you mention, the "cures" are likely going to be targeted gene therapy, maybe stem cells, but your're talking about the brain with it's many neuron types/functions where any drug(s) is likely going to have side affects, so i will likely be too old to take advantage of the cure. we may be doomed to our suffering, maybe not, but as a society, prevention research should be the first priority.

personally for you, i'd find the best mds you can, even if you have to go out of state.