Abby, I honestly think that when MG patients are doing badly it's because the antibodies are busy attacking the NMJ.
And you're right, there is nothing 100% about this disease. Probably why it messes with so many neuro's heads because doctors like things to be predictable. The neuro who diagnosed me once said that he has seen MG patients in a wheelchair test negative to the SFEMG and MG patients who look and are clinically just fine test highly positive on the SFEMG. It would be interesting to compile all of this "negative/positive" info and see how the antibody levels correlate to that - if they even do!
Are there any seropositive patients who've seen their antibodies go down when they get worse? Go up?
Maybe I just have too much time on my hands.
Annie